Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The release of nerve gas in the Tokyo subways, the spread of biological weapons, and the anthrax attack of 2001 in the United States demonstrate that not only is the threat of such menacing weapons real, but also that we must urgently prepare to deal with future acts of bioterrorism. In Biological Weapons Defense: Infectious Diseases and Counterbioterrorism, prominent experts in biodefense research-many from the US Army Medical Research Institute of Infectious Diseases-authoritatively delineate the universe of scientific, medical, and legal issues facing the biodefense research community. Regarding medical countermeasures and decontamination, the authors review the facts about both the aerosol route of infection and decontamination processes, and fully describe the pathogenesis and treatment of a variety of established pathogens (anthrax, plague, smallpox, Brucellosis, glanders, and Coxiella burnetii). They also examine how to discover the presence of these agents, or other previously unknown biological weapons, and the ongoing efforts to counter such agents, including proteomic and genomic analysis as a gateway to better diagnostics, therapeutics, vaccinations, genotyping, and forensics. Additional chapters discuss the development and use of technology to identify and characterize these infectious organisms and their emerging threats. Comprehensive and authoritative, Biological Weapons Defense: Infectious Diseases and Counterbioterrorism provides researchers, physicians, and policymakers with a sound basis for understanding not only the diseases caused by these infectious organisms, but also an appreciation of the universe of bioterrorism problems that must be mastered to develop effective countermeasures.

Bioterrorism --- Communicable Disease Control --- Disaster Planning. --- Bioterrorism. --- Bioterrorisme --- prevention & control. --- methods. --- Public Health Practice --- Biological Warfare --- Investigative Techniques --- Terrorism --- Disasters --- Environment --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Violence --- War --- Public Health --- Crime --- Environment and Public Health --- Social Problems --- Health Care --- Sociology --- Criminology --- Social Sciences --- Anthropology, Education, Sociology and Social Phenomena --- Methods --- Disaster Planning --- Medicine --- Health & Biological Sciences --- Emergency Medicine --- Infectious Diseases --- Bio-terrorism --- Biological terrorism --- Law and legislation --- Political science. --- Medical microbiology. --- Infectious diseases. --- Political Science and International Relations. --- Political Science. --- Infectious Diseases. --- Medical Microbiology. --- Emerging infectious diseases. --- Microbiology. --- Microbial biology --- Biology --- Microorganisms --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Administration --- Civil government --- Commonwealth, The --- Government --- Political theory --- Political thought --- Politics --- Science, Political --- Social sciences --- State, The

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Complement has long been regarded as a pivotal effector arm of the innate immune response, eliciting important immunoregulatory functions in the context of inflammation and also serving as a vital link between the innate and adaptive immune response. In the post-genomic era, our knowledge of the innate immune system is enriched by findings that point to novel functions that do not strictly correlate with immunological defense and surveillance, immune modulation or Inflammation. Several studies indicate that complement proteins exert functions that are either more complex than previously thought, or go well beyond the innate immune character of the system. The advent of high-throughput platforms for genome and proteome-wide profiling, together with the enormous amount of raw genetic information that has accumulated in the databases, have stirred new expectations in biomedical research. They have led complementologists to revisit established biological systems, such as the complement system, from a global and integrative perspective. Complement research is now faced with the challenge of trying to integrate isolated biochemical pathways into complex gene and protein regulatory circuits. In this respect, scientists from around the world convened at the Fourth Aegean Conferences Workshop on Complement Associated Diseases, Animal Models, and Therapeutics (June 10-15, 2007), to discuss recent advances in this fast evolving field. This volume represents a collection of topics on the “novel” functions of complement, patho-physiology, protein structures, design of complement inhibitors, and complement assays discussed during the conference.

Biomedicine. --- Immunology. --- Microbiology. --- Infectious Diseases. --- Pathology. --- Medicine. --- Emerging infectious diseases. --- Médecine --- Immunologie --- Maladies infectieuses émergentes --- Pathologie --- Microbiologie --- Complement (Immunology) -- Congresses. --- Complement (Immunology). --- Complement (Immunology) --- Immunoproteins --- Immune System Processes --- Publication Formats --- Blood Proteins --- Publication Characteristics --- Immune System Phenomena --- Proteins --- Phenomena and Processes --- Amino Acids, Peptides, and Proteins --- Chemicals and Drugs --- Complement System Proteins --- Congresses --- Complement Activation --- Medicine --- Biology --- Health & Biological Sciences --- Medical Research --- Microbiology & Immunology --- Natural immunity --- Disease resistance --- Host resistance --- Innate immunity --- Innate resistance --- Native immunity --- Natural resistance --- Nonspecific immunity --- Resistance to disease --- Alexin --- Complements (Immunity) --- Infectious diseases. --- Microbial biology --- Microorganisms --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine, Preventive --- Immunobiology --- Life sciences --- Serology --- Clinical sciences --- Medical profession --- Human biology --- Pathology --- Physicians --- Immunity --- Blood proteins --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Clustered survival data are encountered in many scientific disciplines including human and veterinary medicine, biology, epidemiology, public health and demography. Frailty models provide a powerful tool to analyse clustered survival data. In contrast to the large number of research publications on frailty models, relatively few statistical software packages contain frailty models. It is demanding for statistical practitioners and graduate students to grasp a good knowledge on frailty models from the existing literature. This book provides an in-depth discussion and explanation of the basics of frailty model methodology for such readers. The discussion includes parametric and semiparametric frailty models and accelerated failure time models. Common techniques to fit frailty models include the EM-algorithm, penalised likelihood techniques, Laplacian integration and Bayesian techniques. More advanced frailty models for hierarchical data are also included. Real-life examples are used to demonstrate how particular frailty models can be fitted and how the results should be interpreted. The programs to fit all the worked-out examples in the book are available from the Springer website with most of the programs developed in the freeware packages R and Winbugs. The book starts with a brief overview of some basic concepts in classical survival analysis, collecting what is needed for the reading on the more complex frailty models. Luc Duchateau is Associate Professor of Statistics at the Faculty of Veterinary Medicine of the Ghent University, Belgium. He is board member of the Quetelet Society (Belgian Region of the International Biometric Society) and of the International Biometric Society Channel Network. He has collaborated extensively with physicians in oncology and allergy, public health workers and veterinarians, and is an author of numerous papers in statistical, medical and veterinarian journals. Paul Janssen is Professor of Statistics at the Centre for Statistics of the Hasselt University, Diepenbeek, Belgium. He is an elected member of the International Statistical Institute. He spent research visits at the Johns Hopkins University (Baltimore, USA) and the University of Washington (Seattle, USA). His research interests include survival analysis, nonparametric estimation, resampling techniques and asymptotic theory.

epidemiologie --- biostatistiek --- Biomathematics. Biometry. Biostatistics --- vormgeving --- besmettelijke ziekten --- Oncology. Neoplasms --- biomathematica --- simulaties --- Artificial intelligence. Robotics. Simulation. Graphics --- oncologie --- Infectious diseases. Communicable diseases --- biometrie --- medische statistiek --- Epidemiology --- Mathematical statistics --- Survival Analysis --- Statistics --- Statistique --- EPUB-LIV-FT LIVSTATI SPRINGER-B --- Statistics. --- 57.087.1 --- 616-036.8 --- Statistical analysis --- Statistical data --- Statistical methods --- Statistical science --- Mathematics --- Econometrics --- 57.087.1 Biometry. Statistical study and treatment of biological data --- Biometry. Statistical study and treatment of biological data --- 616-036.8 Final stage. Termination. Consequences. Results. Successes. Setbacks. Failures. Efficacy. Inefficacy. Survival. Statistics. Mortality in a specific disease --- Final stage. Termination. Consequences. Results. Successes. Setbacks. Failures. Efficacy. Inefficacy. Survival. Statistics. Mortality in a specific disease --- Distribution (Probability theory. --- Oncology. --- Computer simulation. --- Biometry. --- Emerging infectious diseases. --- Probability Theory and Stochastic Processes. --- Statistics for Life Sciences, Medicine, Health Sciences. --- Cancer Research. --- Simulation and Modeling. --- Biometrics. --- Infectious Diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Computer modeling --- Computer models --- Modeling, Computer --- Models, Computer --- Simulation, Computer --- Electromechanical analogies --- Mathematical models --- Simulation methods --- Model-integrated computing --- Tumors --- Distribution functions --- Frequency distribution --- Characteristic functions --- Probabilities --- Biological statistics --- Biology --- Biometrics (Biology) --- Biostatistics --- Biomathematics --- Probabilities. --- Statistics . --- Cancer research. --- Biometrics (Biology). --- Infectious diseases. --- Cancer research --- Probability --- Statistical inference --- Combinations --- Chance --- Least squares --- Risk

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

"Microbiologie en infectieziekten" behandelt alle soorten infecties en alle aandachtsgebieden binnen de medische microbiologie. De indeling van dit boek is gebaseerd op klinische relevante groepen van infectieziekten, waarbij de nadruk is gelegd op die infectieziekten die een in Nederland en Vlaanderen werkzame arts regelmatig tegenkomt. In vergelijking met de voorgaande drukken worden veel ziektebeelden uitgebreider besproken, zijn nieuwe verwekkers opgenomen en is er een hoofdstuk over ooginfecties toegevoegd. Ook is meer aandacht besteed aan de basale aspecten van de medische microbiologie. Het inleidende hoofdstuk is daartoe aanzienlijk uitgebreid en op diverse plaatsen is meer aandacht besteed aan aspecten van het mensenlijke afweersysteem. De hoofdstukken zijn in ruime mate van illustraties voorzien en vrijwel alle ziektebeelden worden toegelicht aan de hand van een patiëntencasus. "Microbiologie en infectieziekten" is primair bedoeld als leerboek voor studenten geneeskunden en medische biologie. Daarnaast is het boek geschikt voor individuele bestudering an als naslagwerk. Aan deze geactualiseerde en uitgebreiede druk hebben specialisten van alle Nederlandse geneeskundefaculteiten meegewerkt.

besmettelijke ziekten --- medische microbiologie --- Infectious diseases. Communicable diseases --- General microbiology --- micro-organismen --- Microbiologie --- Infectieziekten --- 605.11 --- infectieziekten --- microbiologie --- 608.3 --- 579.2 --- 606.4 --- 616.9 --- Ziekten --- infectieziekten, lepra, polio --- Medische microbiologie - Immunologie --- Infectieziekten en SOA --- Besmettelijke ziekten --- Tuberculose --- Otitis --- Griep --- Sinusitis --- Dermatologie --- Seksueel overdraagbare aandoeningen (SOA) --- Aids --- Hepatitis --- Meningitis --- Zwangerschap --- Ziekenhuisinfecties --- Reisziekten --- Medicine. --- Medicine & Public Health. --- Medicine/Public Health, general. --- Microbiology --- Communicable Diseases --- Infectious Diseases --- Communicable Disease --- Disease, Communicable --- Disease, Infectious --- Diseases, Communicable --- Diseases, Infectious --- Infectious Disease --- Disease Outbreaks --- Disease Transmission, Infectious --- Infectious Disease Medicine --- Algemene microbiologie --- Infectieziekten. Besmettelijke ziekten --- HIV infecties --- SOA (seksueel overdraagbare aandoeningen)

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Cet ouvrage traite de l'ensemble des manifestations cutanées et muqueuses observées au cours des différentes maladies infectieuses, métaboliques et toxiques. La première partie aborde de façon exhaustive les manifestations dermatologiques des maladies infectieuses rencontrées dans nos régions, sous les tropiques mais également les pathologies infectieuses émergentes et potentiellement impliquées dans les actes de bioterrorisme. La deuxième partie traite des signes cutanés et muqueux des maladies métaboliques héréditaires et acquises, infantiles et de l'adulte. La troisième partie est consacrée

Dermatology --- Communicable Diseases --- Metabolic Diseases --- Poisoning --- Communicable diseases --- Metabolism --- Dermatologie --- Maladies infectieuses --- Métabolisme, Troubles du --- Empoisonnement --- Disorders --- Dermatology. --- Communicable diseases. --- Métabolisme, Troubles du --- EPUB-LIV-FT LIVMEDEC SPRINGER-B --- Communicable Diseases. --- Metabolic Diseases. --- Poisoning. --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Diseases --- Infection --- Epidemics --- Medicine --- Skin